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GIANT CELLS, LANGHANS
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DeCS
Descriptor
English
:
Giant Cells, Langhans
Descriptor
Spanish
:
Células Gigantes de Langhans
Descriptor
Portuguese
:
Células Gigantes de Langhans
Synonyms
English
:
Cells, Langhans Giant
Cells, Langhans-Type Giant
Giant Cells, Langhans-Type
Langhans Giant Cells
Langhans Type Giant Cells
Langhans-Type Giant Cells
Tree Number:
A11.329.372.380
A11.500.380
A11.627.482.380
A11.733.397.380
A15.382.670.522.380
A15.382.680.397.380
Definition
English
:
Multinucleated cells (fused
macrophages
) seen in granulomatous inflammations such as
tuberculosis
,
syphilis
,
sarcoidosis
, and deep fungal
infections
. They resemble foreign-body
giant cells
(
GIANT CELLS
, FOREIGN BODY) but Langhans
giant cells
contain less
chromatin
and their nuclei are arranged peripherally in a horseshoe-shaped pattern. Langhans
giant cells
occur frequently in delayed
hypersensitivity.
Indexing Annotation
English
:
do not confuse with
LANGERHANS CELLS
nor with
ISLETS OF LANGERHANS
History Note
English
:
91(90); was see under GIANT CELLS 1990
Allowable Qualifiers
English
:
CH
chemistry
CL
classification
CY
cytology
DE
drug effects
EN
enzymology
IM
immunology
ME
metabolism
MI
microbiology
PS
parasitology
PA
pathology
PH
physiology
RE
radiation effects
TR
transplantation
UL
ultrastructure
VI
virology
Record Number:
24696
Unique Identifier:
D015744
Occurrence in VHL
:
Similar:
DeCS